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Clomifene Citrate Description:

Clomid (Clomiphene Citrate) is a powerfully effective anti-estrogen officially classified as a Selective Estrogen Receptor Modulator (SERM). In many ways, it is very similar to another popular SERM in Nolvadex (Tamoxifen Citrate). Clomid first gained worldwide attention in the early 1970’s as a strong fertility aid and is still used for that purpose today. It is also one of the most commonly used SERM’s by anabolic steroid users. No, it is not an anabolic steroid but can be used to combat estrogenic side effects sometimes caused by anabolic steroids. It can also be used as a Post Cycle Therapy (PCT) medication in order to stimulate suppressed testosterone production due to anabolic steroid use. PCT use of Clomid is the most common purpose and most beneficial point of use for the anabolic steroid user.

Clomid is a mixed estrogen agonist/antagonist (activator/blocker) which, when bound to the estrogen receptor, puts it in a somewhat different conformation (shape) than does estradiol. the estrogen receptor requires binding of an estrogen or drug at its binding site and also the binding of any of several cofactors at different sites. without the binding of the cofactor, the estrogen receptor is inactive. different tissues use different cofactors. some of these cofactors are able to bind to the estrogen receptor/clomid complex, but others are blocked due to the change in shape. the result is that in some tissues clomid acts as an antagonist - the cofactor used in that tissue cannot bind and so the receptor remains inactive - and in others clomid acts as an agonist (activator), because the cofactors used in that tissue are able to bind.clomid can play a crucial role in preventing this crash in athletic performance.

As for women, the only real use for clomid is the possible management of endogenous estrogen levels near contest time. this can increase fat loss and muscularity, particularly in female trouble areas such as this hips and thighs. clomid however often produces troubling side effects in women (discussed below), and is likewise not in very high demand among this group of athletes.

Clomid and hcg are also occasionally used periodically during a steroid cycle, in an effort to prevent natural testosterone levels from diminishing. in many instances this practice can prove difficult however, especially when using strong androgens for longer periods of time.

Clomid, or clomiphene citrate, is a serm (selective estrogen receptor modulator), so it’s in the same grouping as tamoxifen (nolvadex). it is the most widely prescribed drug for ovulation induction, which is useful for those who are infertile.

Clomifene Citrate Usage :

Clomiphene Citrate is a SERM that is specifically used as a fertility aid due to its ability to enhance the release of gonadotropins. Clomid has the ability to oppose the negative feedback of estrogens on the Hypothalamic-Pituitary-Ovarian-Axis. This will increase the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) significantly. By increasing gonadotropin release, this can lead to the egg being released, thereby increasing the chance of conception.

Clomid also carries strong anti-estrogen properties that could be used therapeutically, but its anti-estrogen properties are most commonly associated with anabolic steroid use. Testosterone and many testosterone derived steroids have the ability to convert to estrogen through testosterone’s interaction with the aromatase enzyme. As estrogen levels rise, this can lead to gynecomastia and excess water retention. Heavy water retention can also promote high blood pressure. By supplementing with Clomid during anabolic steroid use, the SERM will bind to the estrogen receptors, therefore inhibiting the estrogen hormone from binding. This can be very useful in combating gynecomastia, as when Clomid binds to the receptor it prevents estrogen from stimulating the mammary tissue. It can also have a positive impact on water retention, but as it won’t actively reduce serum estrogen levels it’s sometimes not enough.

Clomid also possess functioning traits that are beneficial to the anabolic steroid user post anabolic steroid use. Specifically we’re referring to Post Cycle Therapy (PCT). In men, Clomid also has the ability to stimulate the pituitary to release more LH and FSH, which will in turn stimulate enhanced natural testosterone production. This is extremely beneficial to the anabolic steroid user post cycle as natural testosterone levels will be very low due to suppression caused by anabolic steroid use.

COA :

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